Ancesol 10 mg/ml Chlorphenamine maleate 100 ml
solution for injection
ACTIVE SUBSTANCE(S) AND OTHER INGREDIENT(S)
1 ml contains:
Chlorphenamine maleate 10 mg
(equivalent to 7.03 mg chlorphenamine)
Methyl parahydroxybenzoate (E218) 1.00 mg
Propyl parahydroxybenzoate 0.20 mg
Clear, colourless to almost colourless solution
For the symptomatic treatment of conditions associated with histamine release.
Do not use in case of hypersensitivity to the active substance or to any of the excipients.
Chlorphenamine has a weak sedative effect.
If you notice any serious effects or other effects not mentioned in this package leaflet, please inform your veterinary surgeon.
DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION
For intramuscular or slow intravenous use, see also section “9. Advice on correct administration”.
0.5 mg Chlorphenamine maleate/kg bodyweight (5 ml/100 kg bodyweight), once a day for three consecutive days.
1 mg Chlorphenamine maleate/kg bodyweight (10 ml/100 kg bodyweight), once a day for three consecutive days.
ADVICE ON CORRECT ADMINISTRATION
Although intravenous administration has an immediate therapeutic effect, it can have excitatory effects on the CNS. Consequently, administer slowly and interrupt administration for a few minutes if necessary, when using this route.
Meat and offal: 24 hours
Milk: 12 hours
SPECIAL STORAGE PRECAUTIONS
Keep out of the sight and reach of children.
Do not use this veterinary medicinal product after the expiry date which is stated on the label and carton after EXP. The expiry date refers to the last day of that month.
Shelf-life after first opening the container: 28 days
After first opening do not store above 30 °C.
Special warnings for each target species
Use during pregnancy and lactation
The safety of the product during pregnancy and lactation has not been established. Use only accordingly to the benefit-risk assessment by the responsible veterinarian.
Interaction with other medicinal products
Concomitant use of other antihistamines or barbiturates may boost the sedative effect of chlorphenamine. The use of antihistamines may conceal early signs of ototoxicity caused by some antibiotics (e.g. aminoglycoside and macrolide antibiotics) and may shorten the effect of oral anticoagulants.
Doses up to four times the therapeutic dose have been well tolerated.
In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician. Do not drive.
Wash splashes from skin and eyes immediately.