Marbocyl 2% is presented as a sterile solution for injection.
Marbofloxacin 2.0% w/v
Disodium edetate 0.01% w/v
Thioglycerol 0.05% w/v
Metacresol 0.2% w/v
In pre-ruminant cattle up to 100kg bodyweight and pigs, Marbofloxacin 2 % is indicated in the treatment of respiratory infections caused by susceptible strains of organisms.
Dosage and administration
The recommended dosage is 2 mg/kg/day (1 ml/10 kg) in a single daily injection by subcutaneous or intravenous routes in cattle and by the intramuscular route in pigs.
Treatment duration is 3 – 5 days by the intravenous route in cattle, 3 days by the subcutaneous route in cattle, and 3 – 5 days by the intramuscular route in pigs.
The volume of injection should be limited to 10ml at each site of injection for pigs.
In order to reduce the risk of particulate contamination of the product, it is recommended that a draw-off needle be used to reduce the number of times the septum is punctured.
Contra-indications, warnings, etc
Special Precautions for use in Animals
Official and local antimicrobial policies should be taken into account when the product is used. Fluoroquinolones should be reserved for the treatment of clinical conditions which have responded poorly, or are expected to respond poorly, to other classes of antimicrobials. Wherever possible, fluoroquinolones should only be used based on susceptibility testing. Use of the product deviating from the instructions given in the SPC may increase the prevalence of bacteria resistant to the fluoroquinolones and may decrease the effectiveness of treatment with other quinolones due to the potential for cross resistance.
No severe side-effects are to be expected at doses up to 5 times the recommended dose in cattle and pigs. In particular no lesions of the articular joints are encountered.
Subcutaneous injection is well tolerated. Transitory inflammatory reactions are sometimes observed at the injection site, but without clinical impact.
Overdosage may cause acute signs in the form of neurological disorders which should be treated symptomatically.